What does the cryptic crossword clue "Wrong dose ain't calming someone down (8)" mean?

The definition is "calming someone down". The wordplay uses an anagram. anagram of DOSE + AIN'T = SEDATION; definition: "calming someone down" The answer is Sedation.

Wrong dose ain't calming someone down (8)

Telegraph Prize Cryptic #3020 | 1 Down | 2019-09-08 flower

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