What does the cryptic crossword clue "Wrongly handle introduction to major issue needing review (6)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Wrongly handle introduction to major issue needing review (6)

Daily Mail Cryptic #17005 | 23 Down | 2023-01-05

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