Across
No saint, unscrupulous individual is filled with constant agitation (9)
I haven't cracked this one yet — but Times for the Times have:
[S]HYSTER, IS with C inserted. Agitation seems a little of an understatement for hysterics, but there you are.
Volume dial adjusted for sound (5)
One handy face card turning up in every deal? (4-2-3-6)
Dull university medic on Scots peak (6)
I haven't cracked this one yet — but Times for the Times have:
BEN (as in Ben Nevis), U [niversity], MB = medic. Dull as a verb, “dull the senses”.
In some way wonder about retaining seat (2,2,4)
Shrub put in particular island area (10)
I haven't cracked this one yet — but Times for the Times have:
POINT, I, A, with SET = put inserted. Particular can be a noun meaning a point, e.g. a detail on a form. An example of this (originally Mexican) plant appears every Christmas in our house, the red and green one, but I’d have spelt it wrongly if you asked me before this clue; it’s not pointsettia, it’s apparently named after an American chap called Joel Robert Poinsett, who was US Minister to Mexico in the 1820s.
Ascend, lopping first branch (4)
Amorously kiss head-turner? (4)
Barbican church away from East in flood (10)
I haven't cracked this one yet — but Times for the Times have:
CH[urch] TO W (away from east) all inside WATER = flood.
Actor, male, scarcely dropping line (3,5)
I haven't cracked this one yet — but Times for the Times have:
I’d never heard of this chap, and pencilled in TOM HANKS at first, until the checkers from 12d forced a rethink and a guess. A TOM is a male cat, and HARDLY loses its L.
Cold hearts in MI6: boss there in breach (6)
I haven't cracked this one yet — but Times for the Times have:
SIS (acronym for Secret Intelligence Service i.e. MI6) has C H (cold, hearts) inserted then M added, she / he being the “boss” of MI6 in Bond movies.
Eurocrat excited with a daring defensive strategy (9,6)
Small border plant in wet ground (5)
Private investigator smart or simple (9)
I haven't cracked this one yet — but Times for the Times have:
well, a private investigator is a (private) eye, and BRIGHT means smart. Eyebright is a common plant used in herbal medicine; such were referred to in Medieval times as “simples”.
Down
Veil what KLM's after with BA on the rise? (5)
I haven't cracked this one yet — but Times for the Times have:
H I J come before K L M in the alphabet; BA reversed.
Deputy with very brief experience at the higher level? (6-2-7)
Finally lose weight — room for eating dessert? (4,4)
I haven't cracked this one yet — but Times for the Times have:
[los]E, TON (weight), MESS where the military can eat. I don’t know if this is a thing apart from in the UK, but my golf club’s chef does a delicious version.
Religious figure present in anima mundi (4)
Talk of flogging tar after beer stashed in ship (5,5)
I haven't cracked this one yet — but Times for the Times have:
ALE in side SS. (steam ship), PITCH = tar.
Truth the ne plus ultra really involves (6)
Palace women win — good Italian side thrashed (6-2-7)
Person belonging to underworld apparently cut to pieces (9)
Dish Keats cooked — one eaten by Hamlet? (5,5)
I haven't cracked this one yet — but Times for the Times have:
(KEATS)*, DANE with I inserted; Hamlet was a Dane.
Such breaches as occasion escape from Tyre? (9)
I haven't cracked this one yet — but Times for the Times have:
I think this is a play on words with Tyre in Lebanon and a tyre on a car (which in USA would be tire and so not work). I thought it might be a reference to some Shakespearean, classical or Biblical quote, but haven’t yet found one.
Frame and beds sent north in strengthened vehicle (5,3)
I haven't cracked this one yet — but Times for the Times have:
COTS reversed, RACK reversed.
Flock on water doubly good in force 8 (6)
Crew set about hauling in new painter (5)
I haven't cracked this one yet — but Times for the Times have:
TEAM reversed with M inserted.
Woodcutter's commercials on radio (4)
Type letters or click words in the clue
